Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson’s disease

Inflammation is one of the pathogenic processes in Parkinson’s disease (PD). Dopamine receptor agonist pramipexole (PPX) is extensively used for PD treatment in clinics. A number of studies show that PPX exerts neuroprotection on dopaminergic (DA) neurons, but the molecular mechanisms underlying the...

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Detalles Bibliográficos
Autores principales: Dong, An-qi, Yang, Ya-ping, Jiang, Shu-min, Yao, Xiao-yu, Qi, Di, Mao, Cheng-jie, Cheng, Xiao-yu, Wang, Fen, Hu, Li-fang, Liu, Chun-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813225/
https://www.ncbi.nlm.nih.gov/pubmed/35896696
http://dx.doi.org/10.1038/s41401-022-00951-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813225/
https://www.ncbi.nlm.nih.gov/pubmed/35896696
http://dx.doi.org/10.1038/s41401-022-00951-1

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