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IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma

BACKGROUNDS: IMPDH1, a rate-limiting enzyme in de novos synthesis of guanine nucleotides, plays an essential role in the growth and progression of certain tumors. However, there is still a lack of study on IMPDH1 evaluating its role in the tumor immune microenvironment, the potential mechanisms, and...

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Detalles Bibliográficos
Autores principales: Liu, Chengdong, Zhang, Wanli, Zhou, Xiaohan, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813230/
https://www.ncbi.nlm.nih.gov/pubmed/36618420
http://dx.doi.org/10.3389/fimmu.2022.983490