Antagonizing cholecystokinin A receptor in the lung attenuates obesity-induced airway hyperresponsiveness

Obesity increases asthma prevalence and severity. However, the underlying mechanisms are poorly understood, and consequently, therapeutic options for asthma patients with obesity remain limited. Here we report that cholecystokinin—a metabolic hormone best known for its role in signaling satiation an...

Descripción completa

Detalles Bibliográficos
Autores principales: Panganiban, Ronald Allan M., Yang, Zhiping, Sun, Maoyun, Park, Chan Young, Kasahara, David I., Schaible, Niccole, Krishnan, Ramaswamy, Kho, Alvin T., Israel, Elliot, Hershenson, Marc B., Weiss, Scott T., Himes, Blanca E., Fredberg, Jeffrey J., Tantisira, Kelan G., Shore, Stephanie A., Lu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813361/
https://www.ncbi.nlm.nih.gov/pubmed/36599824
http://dx.doi.org/10.1038/s41467-022-35739-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813361/
https://www.ncbi.nlm.nih.gov/pubmed/36599824
http://dx.doi.org/10.1038/s41467-022-35739-8

Ejemplares similares