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TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice

Promoting adult neurogenesis in the enteric nervous system (ENS) may be a potential therapeutic approach to cure enteric neuropathies. Enteric glial cells (EGCs) are the most abundant glial cells in the ENS. Accumulating evidence suggests that EGCs can be a complementary source to supply new neurons...

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Detalles Bibliográficos
Autores principales: Shi, Chang-jie, Lian, Jun-jiang, Zhang, Bo-wen, Cha, Jia-xue, Hua, Qiu-hong, Pi, Xiao-ping, Hou, Yu-jun, Xie, Xin, Zhang, Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813375/
https://www.ncbi.nlm.nih.gov/pubmed/35794374
http://dx.doi.org/10.1038/s41401-022-00932-4