Cargando…
TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice
Promoting adult neurogenesis in the enteric nervous system (ENS) may be a potential therapeutic approach to cure enteric neuropathies. Enteric glial cells (EGCs) are the most abundant glial cells in the ENS. Accumulating evidence suggests that EGCs can be a complementary source to supply new neurons...
Autores principales: | Shi, Chang-jie, Lian, Jun-jiang, Zhang, Bo-wen, Cha, Jia-xue, Hua, Qiu-hong, Pi, Xiao-ping, Hou, Yu-jun, Xie, Xin, Zhang, Ru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813375/ https://www.ncbi.nlm.nih.gov/pubmed/35794374 http://dx.doi.org/10.1038/s41401-022-00932-4 |
Ejemplares similares
-
TGF-β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway
por: He, Dengwei, et al.
Publicado: (2021) -
RepSox, a small molecule inhibitor of the TGFβ receptor, induces brown adipogenesis and browning of white adipocytes
por: Tu, Wan-zhi, et al.
Publicado: (2019) -
RepSox effectively promotes the induced differentiation of sheep fibroblasts into adipocytes via the inhibition of the TGF-β1/Smad pathway
por: Guo, Yu, et al.
Publicado: (2021) -
The Multi-Kinase Inhibitor RepSox Enforces Barrier Function in the Face of Both VEGF and Cytokines
por: Lietuvninkas, Lina, et al.
Publicado: (2023) -
A simple method of hiPSCs differentiation into insulin-producing cells is improved with vitamin C and RepSox
por: Horikawa, Ayumi, et al.
Publicado: (2021)