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Effects of dehydroepiandrosterone alone or in combination with a high-fat diet and antibiotic cocktail on the heterogeneous phenotypes of PCOS mouse models by regulating gut microbiota

OBJECTIVE: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disease. The gut microbiota is highly correlated with androgen secretion and insulin resistance (IR), which are two potential major pathogenic mechanisms of PCOS. Currently, an antibiotic cocktail (ABX) is often u...

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Detalles Bibliográficos
Autores principales: Wang, Xuejiao, Gu, Liping, Zhang, Yahui, Xiong, Chuanhao, Peng, Yongde, Ding, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813398/
https://www.ncbi.nlm.nih.gov/pubmed/36619569
http://dx.doi.org/10.3389/fendo.2022.1030151