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Dikkopf-1 promotes matrix mineralization of osteoblasts by regulating Ca(+)-CAMK2A-CREB1 pathway

Dickkopf-1 (DKK1) is a secreted protein that acts as an antagonist of the canonical WNT/β-catenin pathway, which regulates osteoblast differentiation. However, the role of DKK1 on osteoblast differentiation has not yet been fully clarified. Here, we investigate the functional role of DKK1 on osteobl...

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Detalles Bibliográficos
Autores principales: Park, Hyosun, Jo, Sungsin, Jang, Mi-Ae, Choi, Sung Hoon, Kim, Tae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813425/
https://www.ncbi.nlm.nih.gov/pubmed/36229414
http://dx.doi.org/10.5483/BMBRep.2022.55.12.103