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Split genome-based retroviral replicating vectors achieve efficient gene delivery and therapeutic effect in a human glioblastoma xenograft model

The murine leukemia virus-based semi-retroviral replicating vectors (MuLV-based sRRV) had been developed to improve safety and transgene capacity for cancer gene therapy. However, despite the apparent advantages of the sRRV, improvements in the in vivo transduction efficiency are still required to d...

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Detalles Bibliográficos
Autores principales: Kang, Moonkyung, Song, Ayoung, Kim, Jiyoung, Kang, Se Hun, Lee, Sang-Jin, Kim, Yeon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813426/
https://www.ncbi.nlm.nih.gov/pubmed/36195571
http://dx.doi.org/10.5483/BMBRep.2022.55.12.136