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Mettl14 mutation restrains liver regeneration by attenuating mitogens derived from non-parenchymal liver cells

Liver regeneration is a well-known systemic homeostatic phenomenon. The N(6)-methyladenosine (m(6)A) modification pathway has been associated with liver regeneration and hepatocellular carcinoma. m(6)A methyltransferases, such as methyltransferase 3 (METTL3) and methyltransferase 14 (METTL14), are i...

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Detalles Bibliográficos
Autores principales: Yang, Insook, Oh, Seung Yeon, Jang, Suin, Kim, Il Yong, Sung, You Me, Seong, Je Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813429/
https://www.ncbi.nlm.nih.gov/pubmed/36284441
http://dx.doi.org/10.5483/BMBRep.2022.55.12.140