Model for predicting age-dependent safety and immunomodulatory effects of STING ligands in non-human primates

Stimulator of interferon genes (STING) is a cytoplasmic dinucleotide sensor used as an immunomodulatory agent for cancer treatment. The efficacy of the STING ligand (STING-L) against various tumors has been evaluated in mouse models; however, its safety and efficacy in non-human primates have not be...

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Detalles Bibliográficos
Autores principales: Takahama, Shokichi, Ishige, Kazuya, Nogimori, Takuto, Yasutomi, Yasuhiro, Appay, Victor, Yamamoto, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813482/
https://www.ncbi.nlm.nih.gov/pubmed/36620070
http://dx.doi.org/10.1016/j.omtm.2022.12.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813482/
https://www.ncbi.nlm.nih.gov/pubmed/36620070
http://dx.doi.org/10.1016/j.omtm.2022.12.008

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