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Cyclic dinucleotides mediate bacterial immunity by dinucleotide cyclase in Vibrio
The cyclic GMP-AMP (cGAMP) synthase (cGAS) recognizes cytosolic DNA and synthesizes the second messenger, cGAMP, thus activating the adaptor protein stimulator of interferon genes (STING) and initiating the innate immune responses against microbial infections. cGAS-STING pathway has been crucially i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813507/ https://www.ncbi.nlm.nih.gov/pubmed/36619988 http://dx.doi.org/10.3389/fmicb.2022.1065945 |