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Cyclic dinucleotides mediate bacterial immunity by dinucleotide cyclase in Vibrio

The cyclic GMP-AMP (cGAMP) synthase (cGAS) recognizes cytosolic DNA and synthesizes the second messenger, cGAMP, thus activating the adaptor protein stimulator of interferon genes (STING) and initiating the innate immune responses against microbial infections. cGAS-STING pathway has been crucially i...

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Detalles Bibliográficos
Autores principales:	Lu, Zengzeng, Fu, Yuqian, Zhou, Xueyuan, Du, Hekang, Chen, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813507/ https://www.ncbi.nlm.nih.gov/pubmed/36619988 http://dx.doi.org/10.3389/fmicb.2022.1065945

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