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Treatment of congenital thrombocytopenia and decreased collagen reactivity in G6b-B–deficient mice

Mice lacking the immunoreceptor tyrosine-based inhibition motif-containing co-inhibitory receptor G6b-B (Mpig6b, G6b knockout, KO) are born with a complex megakaryocyte (MK) per platelet phenotype, characterized by severe macrothrombocytopenia, expansion of the MK population, and focal myelofibrosis...

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Detalles Bibliográficos
Autores principales:	Mazharian, Alexandra, Maître, Blandine, Bornert, Alicia, Hennequin, Desline, Lourenco-Rodrigues, Marc, Geer, Mitchell J., Smith, Christopher W., Heising, Silke, Walter, Michaela, Montel, Florian, Walker, Lucy S. K., de la Salle, Henri, Watson, Steve P., Gachet, Christian, Senis, Yotis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2022
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813534/ https://www.ncbi.nlm.nih.gov/pubmed/36269841 http://dx.doi.org/10.1182/bloodadvances.2022008873

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