ADAM10 mediates shedding of carbonic anhydrase IX ectodomain non-redundantly to ADAM17

Carbonic anhydrase IX (CA IX) is a transmembrane enzyme participating in adaptive responses of tumors to hypoxia and acidosis. CA IX regulates pH, facilitates metabolic reprogramming, and supports migration, invasion and metastasis of cancer cells. Extracellular domain (ECD) of CA IX can be shed to...

Descripción completa

Detalles Bibliográficos
Autores principales: Zatovicova, Miriam, Kajanova, Ivana, Takacova, Martina, Jelenska, Lenka, Sedlakova, Olga, Labudova, Martina, Pastorekova, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813547/
https://www.ncbi.nlm.nih.gov/pubmed/36524367
http://dx.doi.org/10.3892/or.2022.8464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813547/
https://www.ncbi.nlm.nih.gov/pubmed/36524367
http://dx.doi.org/10.3892/or.2022.8464

Ejemplares similares