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PM2.5 increases susceptibility to acute exacerbation of COPD via NOX4/Nrf2 redox imbalance-mediated mitophagy

The increasing abundance of fine particulate matter (PM2.5) in the environment has increased susceptibility to acute exacerbation of COPD (AECOPD). During PM2.5 exposure, excessive reactive oxygen species (ROS) production triggers a redox imbalance, which contributes to damage to organelles and disr...

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Detalles Bibliográficos
Autores principales: Fan, Xiaoye, Dong, Tingting, Yan, Kun, Ci, Xinxin, Peng, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813701/
https://www.ncbi.nlm.nih.gov/pubmed/36608590
http://dx.doi.org/10.1016/j.redox.2022.102587