Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons

Spinal Muscular Atrophy (SMA) is a genetic neuromuscular disorder caused by reduction of the ubiquitously expressed protein Survival Motor Neuron (SMN). Low levels of SMN impact on spinal cord motoneurons (MNs) causing their degeneration and progressive muscle weakness and atrophy. To study the mole...

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Detalles Bibliográficos
Autores principales: Miralles, Maria P., Sansa, Alba, Beltran, Maria, Soler, Rosa M., Garcera, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813745/
https://www.ncbi.nlm.nih.gov/pubmed/36619669
http://dx.doi.org/10.3389/fncel.2022.1054270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813745/
https://www.ncbi.nlm.nih.gov/pubmed/36619669
http://dx.doi.org/10.3389/fncel.2022.1054270

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