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Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach

Although systemic chemotherapy remains the standard of care for TNBC, even combination chemotherapy is often ineffective. The identification of biomarkers for differential chemotherapy response would allow for the selection of responsive patients, thus maximizing efficacy and minimizing toxicities....

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Detalles Bibliográficos
Autores principales: Petrosyan, Varduhi, Dobrolecki, Lacey E., Thistlethwaite, Lillian, Lewis, Alaina N., Sallas, Christina, Srinivasan, Ramakrishnan R., Lei, Jonathan T., Kovacevic, Vladimir, Obradovic, Predrag, Ellis, Matthew J., Osborne, C. Kent, Rimawi, Mothaffar F., Pavlick, Anne, Shafaee, Maryam Nemati, Dowst, Heidi, Jain, Antrix, Saltzman, Alexander B., Malovannaya, Anna, Marangoni, Elisabetta, Welm, Alana L., Welm, Bryan E., Li, Shunqiang, Wulf, Gerburg M., Sonzogni, Olmo, Huang, Chen, Vasaikar, Suhas, Hilsenbeck, Susan G., Zhang, Bing, Milosavljevic, Aleksandar, Lewis, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813793/
https://www.ncbi.nlm.nih.gov/pubmed/36619972
http://dx.doi.org/10.1016/j.isci.2022.105799