Constructing a polygenic risk score for childhood obesity using functional data analysis

Obesity is a highly heritable condition that affects increasing numbers of adults and, concerningly, of children. However, only a small fraction of its heritability has been attributed to specific genetic variants. These variants are traditionally ascertained from genome-wide association studies (GW...

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Detalles Bibliográficos
Autores principales: Craig, Sarah J.C., Kenney, Ana M., Lin, Junli, Paul, Ian M., Birch, Leann L., Savage, Jennifer S., Marini, Michele E., Chiaromonte, Francesca, Reimherr, Matthew L., Makova, Kateryna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813976/
https://www.ncbi.nlm.nih.gov/pubmed/36620476
http://dx.doi.org/10.1016/j.ecosta.2021.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813976/
https://www.ncbi.nlm.nih.gov/pubmed/36620476
http://dx.doi.org/10.1016/j.ecosta.2021.10.014

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