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Constructing a polygenic risk score for childhood obesity using functional data analysis

Obesity is a highly heritable condition that affects increasing numbers of adults and, concerningly, of children. However, only a small fraction of its heritability has been attributed to specific genetic variants. These variants are traditionally ascertained from genome-wide association studies (GW...

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Detalles Bibliográficos
Autores principales:	Craig, Sarah J.C., Kenney, Ana M., Lin, Junli, Paul, Ian M., Birch, Leann L., Savage, Jennifer S., Marini, Michele E., Chiaromonte, Francesca, Reimherr, Matthew L., Makova, Kateryna D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813976/ https://www.ncbi.nlm.nih.gov/pubmed/36620476 http://dx.doi.org/10.1016/j.ecosta.2021.10.014

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