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The β-cell primary cilium is an autonomous Ca(2+) compartment for paracrine GABA signaling
The primary cilium is an organelle present in most adult mammalian cells that is considered as an antenna for sensing the local microenvironment. Here, we use intact mouse pancreatic islets of Langerhans to investigate signaling properties of the primary cilium in insulin-secreting β-cells. We find...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813980/ https://www.ncbi.nlm.nih.gov/pubmed/36350286 http://dx.doi.org/10.1083/jcb.202108101 |