The β-cell primary cilium is an autonomous Ca(2+) compartment for paracrine GABA signaling

The primary cilium is an organelle present in most adult mammalian cells that is considered as an antenna for sensing the local microenvironment. Here, we use intact mouse pancreatic islets of Langerhans to investigate signaling properties of the primary cilium in insulin-secreting β-cells. We find...

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Detalles Bibliográficos
Autores principales: Sanchez, Gonzalo Manuel, Incedal, Tugce Ceren, Prada, Juan, O’Callaghan, Paul, Dyachok, Oleg, Echeverry, Santiago, Dumral, Özge, Nguyen, Phuoc My, Xie, Beichen, Barg, Sebastian, Kreuger, Johan, Dandekar, Thomas, Idevall-Hagren, Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813980/
https://www.ncbi.nlm.nih.gov/pubmed/36350286
http://dx.doi.org/10.1083/jcb.202108101

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