Tropane and related alkaloid skeletons via a radical [3+3]-annulation process

Tropanes and related bicyclic alkaloids are highly attractive compounds possessing a broad biological activity. Here we report a mild and simple protocol for the synthesis of N-arylated 8-azabicyclo[3.2.1]octane and 9-azabicyclo[3.3.1]nonane derivatives. It provides these valuable bicyclic alkaloid...

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Detalles Bibliográficos
Autores principales: Colson, Eloïse, Andrez, Julie, Dabbous, Ali, Dénès, Fabrice, Maurel, Vincent, Mouesca, Jean-Marie, Renaud, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814087/
https://www.ncbi.nlm.nih.gov/pubmed/36697883
http://dx.doi.org/10.1038/s42004-022-00671-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814087/
https://www.ncbi.nlm.nih.gov/pubmed/36697883
http://dx.doi.org/10.1038/s42004-022-00671-x

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