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Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice

BACKGROUND: Autism spectrum disorder (ASD) is mainly characterized by deficits in social interaction and communication and repetitive behaviors. Known causes of ASD are mutations of certain risk genes like the postsynaptic protein SHANK3 and environmental factors including prenatal infections. METHO...

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Detalles Bibliográficos
Autores principales: Atanasova, Ekaterina, Arévalo, Andrea Pérez, Graf, Ines, Zhang, Rong, Bockmann, Juergen, Lutz, Anne-Kathrin, Boeckers, Tobias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814193/
https://www.ncbi.nlm.nih.gov/pubmed/36604742
http://dx.doi.org/10.1186/s13229-022-00532-3