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Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice
BACKGROUND: Autism spectrum disorder (ASD) is mainly characterized by deficits in social interaction and communication and repetitive behaviors. Known causes of ASD are mutations of certain risk genes like the postsynaptic protein SHANK3 and environmental factors including prenatal infections. METHO...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814193/ https://www.ncbi.nlm.nih.gov/pubmed/36604742 http://dx.doi.org/10.1186/s13229-022-00532-3 |