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N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling

BACKGROUND: Tendon injury is associated with oxidative stress, leading to reactive oxygen species (ROS) production and inflammation. N-acetyl-L-cysteine (NAC) is a potent antioxidant. However, how NAC affects the biological functions of tendon stem/progenitor cells (TSPCs) and tendon repair has not...

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Detalles Bibliográficos
Autores principales: Lu, Kang, Zhou, Mei, Wang, Liyuan, Wang, Yang, Tang, Hong, He, Gang, Wang, Huan, Tang, Chuyue, He, Jie, Wang, Wei, Tang, Kanglai, Wang, Yunjiao, Deng, Zhongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814204/
https://www.ncbi.nlm.nih.gov/pubmed/36604630
http://dx.doi.org/10.1186/s12860-022-00463-0