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Discovery, total syntheses and potent anti-inflammatory activity of pyrrolinone-fused benzoazepine alkaloids Asperazepanones A and B from Aspergillus candidus

Natural products are well established as an important resource and play an important role in drug discovery. Here, two pyrrolinone-fused benzoazepine alkaloids, (+)-asperazepanones A (1) and B (2) with a 6/7/5 ring system, together with the artifact (−)-asperazepanone A (1), were isolated from the c...

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Detalles Bibliográficos
Autores principales: Xu, Li, Guo, Feng-Wei, Zhang, Xue-Qing, Zhou, Tian-Yi, Wang, Chao-Jie, Wei, Mei-Yan, Gu, Yu-Cheng, Wang, Chang-Yun, Shao, Chang-Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814288/
https://www.ncbi.nlm.nih.gov/pubmed/36697682
http://dx.doi.org/10.1038/s42004-022-00696-2