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Navigating the DNA encoded libraries chemical space

DNA-encoded library (DEL) technology is a novel ligand identification strategy that allows the synthesis and screening of unprecedented chemical diversity more efficiently than conventional methods. However, no reports have been published to systematically study how to increase the diversity and imp...

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Detalles Bibliográficos
Autores principales: Martín, Alfredo, Nicolaou, Christos A., Toledo, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814293/
https://www.ncbi.nlm.nih.gov/pubmed/36703354
http://dx.doi.org/10.1038/s42004-020-00374-1