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Pd-catalyzed access to mono- and di-fluoroallylic amines from primary anilines

The Pd-catalyzed highly selective synthesis of mono- and di-2-fluoroallylic amines from gem-difluorocyclopropanes and ubiquitous unprotected primary anilines is herein described. Initial kinetic investigations suggest a first order in the gem-difluorocyclopropane substrate, as well as a circa zeroth...

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Detalles Bibliográficos
Autores principales: Wang, Xingben, Patureau, Frederic W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814328/
https://www.ncbi.nlm.nih.gov/pubmed/36530134
http://dx.doi.org/10.1039/d2cc05844h