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Silver-assisted gold-catalyzed formal synthesis of the anticoagulant Fondaparinux pentasaccharide

Clinically approved anti-coagulant Fondaparinux is safe since it has zero contamination problems often associated with animal based heparins. Fondaparinux is a synthetic pentasaccharide based on the antithrombin-binding domain of Heparin sulfate and contains glucosamine, glucuronic acid and iduronic...

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Detalles Bibliográficos
Autores principales: Walke, Gulab, Kasdekar, Niteshlal, Sutar, Yogesh, Hotha, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814392/
https://www.ncbi.nlm.nih.gov/pubmed/36697540
http://dx.doi.org/10.1038/s42004-021-00452-y