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Silver-assisted gold-catalyzed formal synthesis of the anticoagulant Fondaparinux pentasaccharide
Clinically approved anti-coagulant Fondaparinux is safe since it has zero contamination problems often associated with animal based heparins. Fondaparinux is a synthetic pentasaccharide based on the antithrombin-binding domain of Heparin sulfate and contains glucosamine, glucuronic acid and iduronic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814392/ https://www.ncbi.nlm.nih.gov/pubmed/36697540 http://dx.doi.org/10.1038/s42004-021-00452-y |