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N-Terminal selective modification of peptides and proteins using 2-ethynylbenzaldehydes

Selective modification of the N-terminus of peptides and proteins is a promising strategy for single site modification methods. Here we report N-terminal selective modification of peptides and proteins by using 2-ethynylbenzaldehydes (2-EBA) for the production of well-defined bioconjugates. After re...

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Detalles Bibliográficos
Autores principales: Deng, Jie-Ren, Lai, Nathanael Chun-Him, Kung, Karen Ka-Yan, Yang, Bin, Chung, Sai-Fung, Leung, Alan Siu-Lun, Choi, Man-Chung, Leung, Yun-Chung, Wong, Man-Kin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814395/
https://www.ncbi.nlm.nih.gov/pubmed/36703438
http://dx.doi.org/10.1038/s42004-020-0309-y