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KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2

BACKGROUND: Hepatocellular carcinoma (HCC) is a multifactor-driven malignant tumor with rapid progression, which causes the difficulty to substantially improve the prognosis of HCC. Limited understanding of the mechanisms in HCC impedes the development of efficacious therapies. Despite Krüpple-Like...

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Detalles Bibliográficos
Autores principales: Zhou, Hui, Chen, Junru, Fan, Mingjie, Cai, Huajian, Dong, Yufei, Qiu, Yue, Zhuang, Qianqian, Lei, Zhaoying, Li, Mengyao, Ding, Xue, Yan, Peng, Lin, Aifu, Zheng, Shusen, Yan, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814450/
https://www.ncbi.nlm.nih.gov/pubmed/36600258
http://dx.doi.org/10.1186/s13046-022-02562-4