Phosphorylation regulates the binding of intrinsically disordered proteins via a flexible conformation selection mechanism

Phosphorylation is one of the most common post-translational modifications. The phosphorylation of the kinase-inducible domain (KID), which is an intrinsically disordered protein (IDP), promotes the folding of KID and binding with the KID-interacting domain (KIX). However, the regulation mechanism o...

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Detalles Bibliográficos
Autores principales: Liu, Na, Guo, Yue, Ning, Shangbo, Duan, Mojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814494/
https://www.ncbi.nlm.nih.gov/pubmed/36703366
http://dx.doi.org/10.1038/s42004-020-00370-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814494/
https://www.ncbi.nlm.nih.gov/pubmed/36703366
http://dx.doi.org/10.1038/s42004-020-00370-5

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