Chemoenzymatic synthesis of 3-ethyl-2,5-dimethylpyrazine by L-threonine 3-dehydrogenase and 2-amino-3-ketobutyrate CoA ligase/L-threonine aldolase

Pyrazines are typically formed from amino acids and sugars in chemical reactions such as the Maillard reaction. In this study, we demonstrate that 3-ethyl-2,5-dimethylpyrazine can be produced from L-Thr by a simple bacterial operon. We conclude that EDMP is synthesized chemoenzymatically from L-Thr...

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Detalles Bibliográficos
Autores principales: Motoyama, Tomoharu, Nakano, Shogo, Hasebe, Fumihito, Miyata, Ryo, Kumazawa, Shigenori, Miyoshi, Noriyuki, Ito, Sohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814548/
https://www.ncbi.nlm.nih.gov/pubmed/36697628
http://dx.doi.org/10.1038/s42004-021-00545-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814548/
https://www.ncbi.nlm.nih.gov/pubmed/36697628
http://dx.doi.org/10.1038/s42004-021-00545-8

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