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Asymmetric α-spirocyclopropanation of oxindoles and benzofuranones via dynamic kinetic resolution

Chiral benzo five-membered heterocyclic spirocyclopropanes are an important class of parent core structures with pharmacological activity. A novel organocatalytic one-pot cascade ether oxidation iminium-ion activation strategy for the asymmetric spirocyclopropylation of benzofuran-2-ones and indolin...

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Detalles Bibliográficos
Autores principales: Hu, Yang, Yuan, Jie, Li, Zheyao, Zhao, Lin, Zhao, Jianhong, Yu, Xinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814566/
https://www.ncbi.nlm.nih.gov/pubmed/36697948
http://dx.doi.org/10.1038/s42004-022-00695-3