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Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor
Inhibitors for membrane transporters have been shown to be indispensable as drugs and tool compounds. The proton-dependent oligopeptide transporters PEPT1 and PEPT2 from the SLC15 family play important roles in human and mammalian physiology. With Lys[Z(NO(2))]-Val (LZNV), a modified Lys-Val dipepti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814568/ https://www.ncbi.nlm.nih.gov/pubmed/36697632 http://dx.doi.org/10.1038/s42004-022-00636-0 |