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Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis

Pimarane-type diterpenoids are widely distributed in all domains of life, but no structures or catalytic mechanisms of pimarane-type diterpene synthases (DTSs) have been characterized. Here, we report that two class I DTSs, Sat1646 and Stt4548, each accept copalyl diphosphate (CPP) as the substrate...

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Detalles Bibliográficos
Autores principales: Xing, Baiying, Yu, Jiahui, Chi, Changbiao, Ma, Xueyang, Xu, Qingxia, Li, Annan, Ge, Yuanjie, Wang, Zhengdong, Liu, Tan, Jia, Hongli, Yin, Fuling, Guo, Juan, Huang, Luqi, Yang, Donghui, Ma, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814573/
https://www.ncbi.nlm.nih.gov/pubmed/36697656
http://dx.doi.org/10.1038/s42004-021-00578-z