Scalable total synthesis of (+)-aniduquinolone A and its acid-catalyzed rearrangement to aflaquinolones

The strong antibacterial, antiviral and anticancer activities demonstrated by quinolones make them promising lead structures and important synthetic targets for drug discovery. Here, we report, to the best of our knowledge, the first scalable total synthesis of antiviral (+)-aniduquinolone A, posses...

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Detalles Bibliográficos
Autores principales: Guo, Feng-Wei, Mou, Xiao-Feng, Qu, Yong, Wei, Mei-Yan, Chen, Guang-Ying, Wang, Chang-Yun, Gu, Yu-Cheng, Shao, Chang-Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814574/
https://www.ncbi.nlm.nih.gov/pubmed/36697782
http://dx.doi.org/10.1038/s42004-022-00655-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814574/
https://www.ncbi.nlm.nih.gov/pubmed/36697782
http://dx.doi.org/10.1038/s42004-022-00655-x

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