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Microbial rhodoquinone biosynthesis proceeds via an atypical RquA-catalyzed amino transfer from S-adenosyl-L-methionine to ubiquinone

Rhodoquinone (RQ) is a close analogue of ubiquinone (UQ) that confers diverse bacterial and eukaryotic taxa the ability to utilize fumarate as an electron acceptor in hypoxic conditions. The RquA protein, identified in a Rhodospirillum rubrum RQ-deficient mutant, has been shown to be required for RQ...

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Detalles Bibliográficos
Autores principales: Neupane, Trilok, Chambers, Lydia R., Godfrey, Alexander J., Monlux, Melina M., Jacobs, Evan J., Whitworth, Sophia, Spawn, Jamie E., Clingman, Seo Hee K., Vergunst, Kathleen L., Niven, Fair M., Townley, James J., Orion, Iris W., Goodspeed, Carly R., Cooper, Kathryn A., Cronk, Jeff D., Shepherd, Jennifer N., Langelaan, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814641/
https://www.ncbi.nlm.nih.gov/pubmed/36697674
http://dx.doi.org/10.1038/s42004-022-00711-6