Cargando…

Hydrolysis of 5-methylfuran-2-yl to 2,5-dioxopentanyl allows for stable bio-orthogonal proximity-induced ligation

Ligation methodologies featuring bio-orthogonal units and leading to the formation of a stable adduct are the ideal candidates for being applied in a biological context. However, most of the available strategies rely on highly reactive species that require careful handling, or on the activation of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Manicardi, Alex, Cadoni, Enrico, Madder, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814669/
https://www.ncbi.nlm.nih.gov/pubmed/36697666
http://dx.doi.org/10.1038/s42004-021-00584-1