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Quantifying the binding landscapes of protein–protein interactions

Small changes in protein structure can have pronounced effects on protein–protein interactions, but quantifying this has only recently become possible. Now, the binding landscapes of three homologous enzyme–inhibitor complexes are quantified and shown to depend on whether the inhibitor binds its nat...

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Detalles Bibliográficos
Autor principal: Bissette, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814691/
https://www.ncbi.nlm.nih.gov/pubmed/36697583
http://dx.doi.org/10.1038/s42004-021-00608-w