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Extracellular protein degradation via the lysosome
Tight regulation of protein levels is so crucial for cellular function that mammalian cells have evolved two parallel degradation systems. This article discusses how these systems can be exploited to selectively target proteins of interest for therapeutic purposes.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814758/ https://www.ncbi.nlm.nih.gov/pubmed/36703340 http://dx.doi.org/10.1038/s42004-020-00397-8 |