Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group

Escherichia coli glutamate decarboxylase (EcGadB), a pyridoxal 5’-phosphate (PLP)-dependent enzyme, is highly specific for L-glutamate and was demonstrated to be effectively immobilised for the production of γ-aminobutyric acid (GABA), its decarboxylation product. Herein we show that EcGadB quantita...

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Detalles Bibliográficos
Autores principales: De Biase, Daniela, Cappadocio, Francesca, Pennacchietti, Eugenia, Giovannercole, Fabio, Coluccia, Antonio, Vepsäläinen, Jouko, Khomutov, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814759/
https://www.ncbi.nlm.nih.gov/pubmed/36703359
http://dx.doi.org/10.1038/s42004-020-00368-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814759/
https://www.ncbi.nlm.nih.gov/pubmed/36703359
http://dx.doi.org/10.1038/s42004-020-00368-z

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