Intrastriatal injection of Parkinson’s disease intestine and vagus lysates initiates α-synucleinopathy in rat brain

Parkinson’s disease (PD) is characterized by the selective loss of dopaminergic neurons in the midbrain and the pathological accumulation of misfolded α-synuclein (α-syn) in the brain. A growing body of evidence suggests that the formation of misfolded α-syn and aggregation may begin in the peripher...

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Detalles Bibliográficos
Autores principales: Yang, Zhaofei, Wang, Ying, Wei, Min, Li, Song, Jia, Congcong, Cheng, Cheng, Al-Nusaif, Murad, Zhang, Jun, Liu, Cong, Le, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814765/
https://www.ncbi.nlm.nih.gov/pubmed/36604420
http://dx.doi.org/10.1038/s41419-022-05531-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814765/
https://www.ncbi.nlm.nih.gov/pubmed/36604420
http://dx.doi.org/10.1038/s41419-022-05531-z

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