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Converting histidine-induced 3D protein arrays in crystals into their 3D analogues in solution by metal coordination cross-linking

Histidine (His) residues represent versatile motifs for designing protein-protein interactions because the protonation state of the imidazole group of His is the only moiety in protein to be significantly pH dependent under physiological conditions. Here we show that, by the designed His motifs near...

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Detalles Bibliográficos
Autores principales: Tan, Xiaoyi, Chen, Hai, Gu, Chunkai, Zang, Jiachen, Zhang, Tuo, Wang, Hongfei, Zhao, Guanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814774/
https://www.ncbi.nlm.nih.gov/pubmed/36703383
http://dx.doi.org/10.1038/s42004-020-00394-x