Multivariate effects of pH, salt, and Zn(2+) ions on Aβ(40) fibrillation

Amyloid-β (Aβ) peptide aggregation plays a central role in the progress of Alzheimer’s disease (AD), of which Aβ-deposited extracellular amyloid plaques are a major hallmark. The brain micro-environmental variation in AD patients, like local acidification, increased ionic strength, or changed metal...

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Detalles Bibliográficos
Autores principales: Wang, Hongzhi, Wu, Jinming, Sternke-Hoffmann, Rebecca, Zheng, Wenwei, Mörman, Cecilia, Luo, Jinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814776/
https://www.ncbi.nlm.nih.gov/pubmed/36697708
http://dx.doi.org/10.1038/s42004-022-00786-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814776/
https://www.ncbi.nlm.nih.gov/pubmed/36697708
http://dx.doi.org/10.1038/s42004-022-00786-1

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