Cargando…

Multivariate effects of pH, salt, and Zn(2+) ions on Aβ(40) fibrillation

Amyloid-β (Aβ) peptide aggregation plays a central role in the progress of Alzheimer’s disease (AD), of which Aβ-deposited extracellular amyloid plaques are a major hallmark. The brain micro-environmental variation in AD patients, like local acidification, increased ionic strength, or changed metal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Hongzhi, Wu, Jinming, Sternke-Hoffmann, Rebecca, Zheng, Wenwei, Mörman, Cecilia, Luo, Jinghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814776/ https://www.ncbi.nlm.nih.gov/pubmed/36697708 http://dx.doi.org/10.1038/s42004-022-00786-1

Ejemplares similares

The Aggregation Conditions Define Whether EGCG is an Inhibitor or Enhancer of α-Synuclein Amyloid Fibril Formation
por: Sternke-Hoffmann, Rebecca, et al.
Publicado: (2020)

Zn salts incorporated polyurethane/polyacrylonitrile electrospinning fiber membrane for high porosity polymer electrolyte in Zn ion battery
por: Likitaporn, Chutiwat, et al.
Publicado: (2023)

Computational screening of nanoparticles coupling to Aβ40 peptides and fibrils
por: Sen, Soumyo, et al.
Publicado: (2019)

pH-controlled stacking direction of the β-strands in peptide fibrils
por: Tseng, Wei-Hsuan, et al.
Publicado: (2020)

Ion mobility spectrometry combined with multivariate statistical analysis: revealing the effects of a drug candidate for Alzheimer’s disease on Aβ1-40 peptide early assembly
por: Lazzaro, Serena, et al.
Publicado: (2019)

Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia
por: Zhu, Xiaoyue, et al.
Publicado: (2022)

Molecular Origins of the Compatibility between Glycosaminoglycans and Aβ40 Amyloid Fibrils
por: Stewart, Katie L., et al.
Publicado: (2017)

Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer’s Disease
por: Abelein, Axel, et al.
Publicado: (2022)

Aβ-40 Y10F Increases βfibrils Formation but Attenuates the Neurotoxicity of Amyloid-β Peptide
por: Dai, Xueling, et al.
Publicado: (2012)

Nanoscale Structure and Spectroscopic Probing of Aβ1-40 Fibril Bundle Formation
por: Psonka-Antonczyk, Katarzyna M., et al.
Publicado: (2016)

PhSeZnCl in the Synthesis of Steroidal β-Hydroxy-Phenylselenides Having Antibacterial Activity
por: Jastrzebska, Izabella, et al.
Publicado: (2019)

Fibrillization of 40-residue β-Amyloid Peptides in Membrane-Like Environments Leads to Different Fibril Structures and Reduced Molecular Polymorphisms
por: Cheng, Qinghui, et al.
Publicado: (2020)

Interactions of Zn(II) Ions with Humic Acids Isolated from Various Type of Soils. Effect of pH, Zn Concentrations and Humic Acids Chemical Properties
por: Boguta, Patrycja, et al.
Publicado: (2016)

β(2)-Microglobulin Amyloid Fibril-Induced Membrane Disruption Is Enhanced by Endosomal Lipids and Acidic pH
por: Goodchild, Sophia C., et al.
Publicado: (2014)

Computational Insight into the Effect of Natural Compounds on the Destabilization of Preformed Amyloid-β(1–40) Fibrils
por: Tavanti, Francesco, et al.
Publicado: (2018)

Peptide backbone modifications of amyloid β (1–40) impact fibrillation behavior and neuronal toxicity
por: Schwarze, Benedikt, et al.
Publicado: (2021)

Fast ion transport for synthesis and stabilization of β-Zn(4)Sb(3)
por: Yang, Dongwang, et al.
Publicado: (2021)

Current-Density Calculations on Zn-Porphyrin(40) Nanorings
por: Mahmood, Atif, et al.
Publicado: (2023)

The Environment Is a Key Factor in Determining the Anti-Amyloid Efficacy of EGCG
por: Sneideris, Tomas, et al.
Publicado: (2019)

The role of conformational flexibility in β(2)-microglobulin amyloid fibril formation at neutral pH
por: Hodkinson, John P, et al.
Publicado: (2012)

pH Dependence of Amyloid‐β Fibril Assembly Kinetics: Unravelling the Microscopic Molecular Processes
por: Tian, Yao, et al.
Publicado: (2022)

Amyloid-beta–copper interaction studied by simultaneous nitrogen K and copper L(2,3)(-)edge soft X-ray absorption spectroscopy
por: Luo, Jinghui, et al.
Publicado: (2021)

A Better Zn-Ion Storage Device: Recent Progress for Zn-Ion Hybrid Supercapacitors
por: Jin, Jialun, et al.
Publicado: (2022)

(13)C- and (15)N-labeling of amyloid-β and inhibitory peptides to study their interaction via nanoscale infrared spectroscopy
por: Paul, Suman, et al.
Publicado: (2023)

1,5‐Diazacyclooctanes, as Exclusive Oxidative Polyamine Metabolites, Inhibit Amyloid‐β(1‐40) Fibrillization
por: Tsutsui, Ayumi, et al.
Publicado: (2016)

Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aβ40 fibrils
por: Irizarry, Brandon A., et al.
Publicado: (2021)

The role of ion exchange in the passivation of In(Zn)P nanocrystals with ZnS
por: Cho, Deok-Yong, et al.
Publicado: (2016)

The (40)Ca(+) ion optical clock
por: Gao, Kelin
Publicado: (2020)

Salt as a Trigger for Atrial Tachycardia/Fibrillation
por: Goddard, Jerome, et al.
Publicado: (2022)

The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments
por: Król, Sylwia, et al.
Publicado: (2021)

Few Ramachandran Angle Changes Provide Interaction Strength Increase in Aβ42 versus Aβ40 Amyloid Fibrils
por: Bastidas, Oscar H., et al.
Publicado: (2016)

Biochemical and biophysical characterisation of immunoglobulin free light chains derived from an initially unbiased population of patients with light chain disease
por: Sternke-Hoffmann, Rebecca, et al.
Publicado: (2020)

Molecular Structures of Quiescently Grown and Brain-Derived Polymorphic Fibrils of the Alzheimer Amyloid Aβ(9-40) Peptide: A Comparison to Agitated Fibrils
por: Wu, Chun, et al.
Publicado: (2010)

Intermediate antiparallel fibrils in Aβ40 Dutch mutant aggregation: nanoscale insights from AFM-IR
por: Banerjee, Siddhartha, et al.
Publicado: (2023)

Mercury and Alzheimer’s Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization
por: Wallin, Cecilia, et al.
Publicado: (2019)

Effect of ph and salt gradient on the autolysis of Lactococcus lactis strains
por: Ramírez-Nuñez, Jennifer, et al.
Publicado: (2011)

Unusual Salt and pH Induced Changes in Polyethylenimine Solutions
por: Curtis, Kimberly A., et al.
Publicado: (2016)

Efficacy of ZnO nanoparticles in Zn fortification and partitioning of wheat and rice grains under salt stress
por: Mazhar, Zuhra, et al.
Publicado: (2023)

Molecular Dynamics Study of Zn(Aβ) and Zn(Aβ)(2)
por: Pan, Lurong, et al.
Publicado: (2013)

Aquaculture 4.0: hybrid neural network multivariate water quality parameters forecasting model
por: Eze, Elias, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f5f8b3nkr3qhpr8irhh5bm0gs7