A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice

Non-alcoholic steatohepatitis (NASH) - a hepatic manifestation of the metabolic syndrome - is a multifactorial disease with alarming global prevalence. It involves steatosis, inflammation and fibrosis in the liver, thus demanding multiple modes of action for robust therapeutic efficacy. Aiming to fu...

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Detalles Bibliográficos
Autores principales: Heitel, Pascal, Faudone, Giuseppe, Helmstädter, Moritz, Schmidt, Jurema, Kaiser, Astrid, Tjaden, Amelie, Schröder, Martin, Müller, Susanne, Schierle, Simone, Pollinger, Julius, Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814779/
https://www.ncbi.nlm.nih.gov/pubmed/36703463
http://dx.doi.org/10.1038/s42004-020-00411-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814779/
https://www.ncbi.nlm.nih.gov/pubmed/36703463
http://dx.doi.org/10.1038/s42004-020-00411-z

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