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Mapping protein glycosylation through oxocarbenium ion generation
Mass spectrometry allows the pattern of glycosylation in proteins to be mapped, but can be limited by the lability of glycosidic bonds. Now, a method exploiting this lability allows for direct mapping of glycan moieties in glycoproteins.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814829/ https://www.ncbi.nlm.nih.gov/pubmed/36703321 http://dx.doi.org/10.1038/s42004-020-00352-7 |