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Mapping protein glycosylation through oxocarbenium ion generation

Mass spectrometry allows the pattern of glycosylation in proteins to be mapped, but can be limited by the lability of glycosidic bonds. Now, a method exploiting this lability allows for direct mapping of glycan moieties in glycoproteins.

Detalles Bibliográficos
Autor principal: Bissette, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814829/
https://www.ncbi.nlm.nih.gov/pubmed/36703321
http://dx.doi.org/10.1038/s42004-020-00352-7