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NHC-Ni catalyzed 1,3- and 1,4-diastereodivergent heterocycle synthesis from hetero-substituted enyne

Diastereodivergent heterocycle synthesis has been recognized as an important tool for drug discovery in recent years, yet strategies based on nickelacycle formation have not been established. Here, we report a NHC-Ni catalyzed highly 1,3- and 1,4-diastereodivergent heterocycle synthesis from enyne,...

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Detalles Bibliográficos
Autores principales: Yong, Xuefeng, Gao, Weiwei, Lin, Xiulian, Ho, Chun-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814851/
https://www.ncbi.nlm.nih.gov/pubmed/36703443
http://dx.doi.org/10.1038/s42004-020-0299-9