Cargando…

Ancestral L-amino acid oxidases for deracemization and stereoinversion of amino acids

L-amino acid oxidases (LAAOs) can be applied to convert racemic amino acids to D-isomers, which are potential precursors of pharmaceuticals. However, this application is hampered by the lack of available stable and structure-determined LAAOs. In this study, we attempt to address this limitation by u...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakano, Shogo, Kozuka, Kohei, Minamino, Yuki, Karasuda, Hiroka, Hasebe, Fumihito, Ito, Sohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814856/
https://www.ncbi.nlm.nih.gov/pubmed/36703379
http://dx.doi.org/10.1038/s42004-020-00432-8